A Practical Guide to Managing Digestion with GLP-1 Medications

Kokomo Kim, CEO, IPHM, Practitioner of Holistic Medicine

4 min read

GLP-1 medications are powerful tools for improving metabolic health, controlling appetite, and supporting weight loss. However, they can slow gastric emptying, which may feel unfamiliar or uncomfortable for some. This guide explains why this effect is beneficial and how you can manage digestion effectively while on GLP-1s.

How GLP-1s Impact Digestion

1. The Normal Process of Gastric Emptying

In a typical digestive process, food moves steadily from the stomach to the intestines, allowing for nutrient absorption and blood sugar regulation.

2. How GLP-1s Change This Process

These medications slow the rate at which food leaves the stomach, helping to stabilize blood sugar levels, control hunger, and create a longer-lasting feeling of fullness.

3. Why It Feels Different

A slower digestive process can cause sensations like bloating, mild discomfort, or feeling overly full after eating. These effects are manageable with the right strategies.

4. Is It Harmful?

For most individuals, no. The slower emptying of the stomach is part of how GLP-1s support appetite regulation and weight loss.

5. How to Address Discomfort

- Focus on smaller, more frequent meals.

- Use digestive enzymes to help break down food more efficiently.

- Stay hydrated and consider magnesium or electrolytes to avoid constipation.

- Try apple cider vinegar (ACV) or betaine HCl before meals to support protein digestion.

Optimizing Digestion on GLP-1 Medications

1. Prepare Your Digestive System

Since digestion slows, your body may need extra support before meals to process food effectively:

Digestive Enzymes and Acids

Help your stomach break down macronutrients with:

Betaine HCl + Pepsin (helps digest proteins).

Ox Bile or TUDCA (supports fat digestion).

Pancreatic Enzymes (general support for all macronutrients).

Apple Cider Vinegar or Lemon Water

Drinking 1 tbsp of ACV or lemon water before meals can stimulate stomach acid production and aid digestion.

Pre-Meal Movement

A quick 5-minute brisk walk before eating can improve insulin sensitivity and enhance digestive motility.

2. Choose Foods That Are Easier to Digest

Selecting the right foods can reduce digestive strain and discomfort:

Protein

Opt for lean meats like chicken, turkey, or fish.

Eggs and collagen protein are also gentle on the stomach.

Carbohydrates

Choose easily digestible carbs like white rice, sweet potatoes, or berries.

Favor well-cooked vegetables like zucchini, squash, or carrots over raw, fibrous options.

Fats

Use medium-chain triglycerides (MCTs) from coconut oil, which are easier to digest.

Avocado and olive oil are also excellent choices. Avoid inflammatory seed oils.

Gut-Healing Additions

Bone Broth: Provides electrolytes and supports gut lining repair.

Fermented Foods: Items like kimchi or sauerkraut offer probiotics for gut health.

3. Use Targeted Supplements

Supplements can help prevent common side effects like bloating, constipation, or sluggish digestion:

For Constipation

Magnesium Citrate (200-400mg at night): Encourages bowel movements.

Tributyrin (Butyrate): Supports gut metabolism and motility.

For Gas and Bloating

Activated Charcoal: Absorbs excess gas and toxins.

Fennel or Ginger Tea: Soothes the digestive system and reduces bloating.

For Gut Health

Probiotics: Maintain a healthy gut microbiome.

Prebiotics: Feed beneficial bacteria with resistant starch or acacia fiber.

Post-Meal Strategies for Better Digestion

1. Go for a 10-minute walk after meals to promote motility and reduce bloating.

2. Practice deep breathing exercises to relax the stomach and reduce discomfort.

3. Avoid lying down or sitting for extended periods immediately after eating.

Adjusting Your GLP-1 Dosing

If digestive side effects become too challenging:

Start with a lower dose and gradually increase it.

Pair the medication with mitochondrial boosters for added energy and digestive support.

Affordable GLP-1 Options with Life RX Md

If you’re looking for a cost-effective GLP-1 provider, Life RX Md offers:

Compounded Semaglutide for $225 flat rate, including all doses, supplies, and education.

Telehealth visits for just $49.95 initially, with follow-ups every 90 days for $25.

Use coupon code KOKOMO to save $50 off your first month.

Optional $30 shipping with no contracts or hidden fees.

Final Thoughts: A Balanced Approach

By following these strategies, you can enjoy the benefits of GLP-1 medications without discomfort:

Prepare your digestive system with enzymes, ACV, and pre-meal walks.

Choose foods that are gentle on digestion, like lean proteins, simple carbs, and healthy fats.

Use supplements to address constipation, bloating, and gut health.

Stay active after meals to support motility.

Adjust your dosage if necessary to minimize side effects.

With the right approach, you can fully experience the appetite control, metabolic, and fat loss benefits of GLP-1s. Slower gastric emptying doesn’t have to be a drawback—it’s part of the process that helps you succeed!

Disclaimer: This is not medical advice. This content is for patient education and entertainment purposes only. Always consult with your healthcare provider before making any changes to your medication or health routine.

Written by, Kokomo Kim

CEO, C-IPHM, Executive Therapist

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